Ehrnhoefer, Dagmar E. : rechercher sur Z-Library

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1

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

Ehrnhoefer, Dagmar E, Bieschke, Jan, Boeddrich, Annett, Herbst, Martin, Masino, Laura, Lurz, Rudi, Engemann, Sabine, Pastore, Annalisa, Wanker, Erich E

Journal:

Nature Structural and Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2008

2

Autophagy in Huntington disease and huntingtin in autophagy

Martin, Dale D.O., Ladha, Safia, Ehrnhoefer, Dagmar E., Hayden, Michael R.

Journal:

Trends in Neurosciences

Année:

2015

Langue:

english

Fichier:

PDF, 713 KB

english, 2015

3

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

Ehrnhoefer, Dagmar E., Martin, Dale D. O., Schmidt, Mandi E., Qiu, Xiaofan, Ladha, Safia, Caron, Nicholas S., Skotte, Niels H., Nguyen, Yen T. N., Vaid, Kuljeet, Southwell, Amber L., Engemann, Sabine,

Journal:

Acta Neuropathologica Communications

Année:

2018

Langue:

english

Fichier:

PDF, 4.15 MB

english, 2018

4

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease

Jeffrey B Carroll, Amber L Southwell, Rona K Graham, Jason P Lerch, Dagmar E Ehrnhoefer, Li-Ping Cao, Wei-Ning Zhang, Yu Deng, Nagat Bissada, R Mark Henkelman, Michael R Hayden

Journal:

Molecular Neurodegeneration

Année:

2011

Langue:

english

Fichier:

PDF, 440 KB

english, 2011

5

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

Okamoto, Shu-ichi, Pouladi, Mahmoud A, Talantova, Maria, Yao, Dongdong, Xia, Peng, Ehrnhoefer, Dagmar E, Zaidi, Rameez, Clemente, Arjay, Kaul, Marcus, Graham, Rona K

Journal:

Nature Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 858 KB

english, 2009

6

Caspase-6 and neurodegeneration

Rona K. Graham, Dagmar E. Ehrnhoefer, Michael R. Hayden

Journal:

Trends in Neurosciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2011

7

Convergent pathogenic pathways in Alzheimer's and Huntington's diseases: shared targets for drug development

Ehrnhoefer, Dagmar E., Wong, Bibiana K. Y., Hayden, Michael R.

Journal:

Nature Reviews Drug Discovery

Année:

2011

Langue:

english

Fichier:

PDF, 968 KB

english, 2011

8

NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease

Pouladi, Mahmoud A., Brillaud, Elsa, Xie, Yuanyun, Conforti, Paola, Graham, Rona K., Ehrnhoefer, Dagmar E., Franciosi, Sonia, Zhang, Weining, Poucheret, Patrick, Compte, Elsa, Maurel, Jean-Claude, Zuc

Journal:

Neurobiology of Disease

Année:

2012

Langue:

english

Fichier:

PDF, 601 KB

english, 2012

9

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Bieschke, Jan, Russ, Jenny, Friedrich, Ralf P., Ehrnhoefer, Dagmar E., Wobst, Heike, Neugebauer, Katja, Wanker, Erich E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 830 KB

english, 2010

10

Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice

Wong, Bibiana K.Y., Ehrnhoefer, Dagmar E., Graham, Rona K., Martin, Dale D.O., Ladha, Safia, Uribe, Valeria, Stanek, Lisa M., Franciosi, Sonia, Qiu, Xiaofan, Deng, Yu, Kovalik, Vlad, Zhang, Weining, P

Journal:

Neurobiology of Disease

Année:

2015

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2015

11

Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD

Riechers, Sean-Patrick, Butland, Stefanie, Deng, Yu, Skotte, Niels, Ehrnhoefer, Dagmar E., Russ, Jenny, Laine, Jean, Laroche, Melissa, Pouladi, Mahmoud A., Wanker, Erich E., Hayden, Michael R., Graham

Journal:

Human Molecular Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2016

12

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Jan Bieschke, Jenny Russ, Ralf P. Friedrich, Dagmar E. Ehrnhoefer, Heike Wobst, Katja Neugebauer, Erich E. Wanker and Susan Lindquist

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2010

13

Laquinimod decreases Bax expression and reduces caspase-6 activation in neurons

Ehrnhoefer, Dagmar E., Caron, Nicholas S., Deng, Yu, Qiu, Xiaofan, Tsang, Michelle, Hayden, Michael R.

Journal:

Experimental Neurology

Année:

2016

Langue:

english

Fichier:

PDF, 863 KB

english, 2016

14

Palmitoylation of caspase-6 by HIP14 regulates its activation

Skotte, Niels H, Sanders, Shaun S, Singaraja, Roshni R, Ehrnhoefer, Dagmar E, Vaid, Kuljeet, Qiu, Xiaofan, Kannan, Srinivasaragavan, Verma, Chandra, Hayden, Michael R

Journal:

Cell Death & Differentiation

Année:

2016

Langue:

english

Fichier:

PDF, 2.76 MB

english, 2016

15

HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo

Ehrnhoefer, Dagmar E, Southwell, Amber L, Sivasubramanian, Meenalochani, Qiu, Xiaofan, Villanueva, Erika B, Xie, Yuanyun, Waltl, Sabine, Anderson, Lisa, Fazeli, Anita, Casal, Lorenzo, Felczak, Bogusla

Journal:

Human Molecular Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 891 KB

english, 2018

16

Constitutive ablation of caspase-6 reduces the inflammatory response and behavioural changes caused by peripheral pro-inflammatory stimuli

Ladha, Safia, Qiu, Xiaofan, Casal, Lorenzo, Caron, Nicholas S., Ehrnhoefer, Dagmar E., Hayden, Michael R.

Journal:

Cell Death Discovery

Année:

2018

Langue:

english

Fichier:

PDF, 725 KB

english, 2018

17

A validated antibody panel for the characterization of tau post-translational modifications

Ercan, Ebru, Eid, Sameh, Weber, Christian, Kowalski, Alexandra, Bichmann, Maria, Behrendt, Annika, Matthes, Frank, Krauss, Sybille, Reinhardt, Peter, Fulle, Simone, Ehrnhoefer, Dagmar E.

Journal:

Molecular Neurodegeneration

Année:

2017

Langue:

english

Fichier:

PDF, 9.86 MB

english, 2017

18

Generation of an induced pluripotent stem cell cohort suitable to investigate sporadic Alzheimer's Disease

Schöndorf, David C., Elschami, Myriam, Schieck, Maximilian, Ercan-Herbst, Ebru, Weber, Christian, Riesinger, Yasmin, Kalman, Sara, Steinemann, Doris, Ehrnhoefer, Dagmar E.

Journal:

Stem Cell Research

Année:

2019

Langue:

english

Fichier:

PDF, 984 KB

english, 2019

19

A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain

Ercan-Herbst, Ebru, Ehrig, Jens, Schöndorf, David C., Behrendt, Annika, Klaus, Bernd, Gomez Ramos, Borja, Prat Oriol, Nuria, Weber, Christian, Ehrnhoefer, Dagmar E.

Journal:

Acta Neuropathologica Communications

Année:

2019

Fichier:

PDF, 2.72 MB

2019

20

Compromised IGF signaling causes caspase-6 activation in Huntington disease

Skotte, Niels Henning, Pouladi, Mahmoud A., Ehrnhoefer, Dagmar E., Huynh, Katie, Qiu, Xiaofan, Nielsen, Signe Marie Borch, Nielsen, Troels Tolstrup, NÃ¸rremÃ¸lle, Anne, Hayden, Michael R.

Journal:

Experimental Neurology

Année:

2020

Fichier:

PDF, 5.46 MB

2020